TARCC Research Leadership PDF Print E-mail

Each of the following six major medical research institutions participating in the Texas Alzheimer’s Research and Care Consortium is represented on a Steering Committee of leading Alzheimer’s researchers:

Baylor College of Medicine
Texas Tech University Health Sciences Center
University of North Texas Health Science Center
The University of Texas Health Sciences Center at San Antonio
The University of Texas Southwestern Medical Center
Texas A & M Health Science Center

The Steering Committee sets research priorities and policies, and works with Consortium staff to coordinate data collection, research activities, and reporting of findings among the participating medical schools and health science centers.

About two dozen AD researchers from across Texas participate in the Consortium’s work. Many serve on TARCC’s Biomarker, Genetics and Neuropsychology Subcommittees. TARCC Project Coordinator Jim Hinds and Dr. Robert Barber, TARCC Scientific Manager, provide staff support to ensure the Consortium’s research goals are met.

Baylor College of Medicine, Houston

Rachelle Doody, M.D., Ph.D.

Rachelle Doody, M.D., Ph.D., is the Effie Marie Cain Chair in Alzheimer’s Disease Research, and Professor of Neurology in the Department of Neurology at Baylor College of Medicine in Houston. She received a Ph.D. in Cognitive Anthropology from Rice University where she studied the brain and language. She earned a M.D. from Baylor College of Medicine, and completed her internship and residency training there and at the Royal Victoria Hospital and Montreal Neurologic Institute in Montreal. She has authored more than 100 publications, most of which deal with the diagnosis, progression, or treatment of Alzheimer’s disease and related disorders, and is a featured speaker at national and international conferences devoted to research on AD and other dementias. She has received multiple research grants, including a Zenith Award from the National Alzheimer’s Association.

Primary Research Interests: Cognitive aspects of Alzheimer's disease, dementia, and aphasia; Alzheimer's disease therapeutics and modeling of progression for clinical prognostication, validation of biological markers, and enhancing design of AD clinical trials.

TARCC Scientific Committees: Steering Committee
Dr. Doody's publications on PubMed
Curriculm Vitae


Texas A & M Health Science Center, Bryan

Farida Sohrabji, Ph.D. Farida Sohrabji, Ph.D., is the Joseph H. Shelton Professor of Neuroscience, Associate Department Chair of Neuroscience and Experimental Therapeutics, and Director of the Women’s Health in Neuroscience Program at the Texas A&M Health Science Center College of Medicine. She earned a joint doctoral degree in Neurobiology & Biopsychology from the University of Rochester New York, and obtained and completed her post-doctoral training in Neuroendocrinology at Columbia University, College of Physicians and Surgeons (New York, NY). Dr. Sohrabji joined the faculty of Texas A&M Health Science Center College of Medicine in 1998. Dr. Sohrabji directs a federally funded research program that focuses on age-related changes in brain health, specifically, neuroinflammation, cerebral ischemia and brain-immune interactions and the impact of estrogen and hormone replacement. She is also the recipient of a grant from the National Alzheimer’s Association to study the effects of estrogen and estrogen receptor specific ligands on neural inflammation. Dr. Sohrabji serves on the Advisory Council on Research on Women’s Health (ORWH), on NIH scientific review panels and the Editorial board of Endocrinology, and is Treasurer of the Organization for the Study of Sex Differences.

Primary Research Interests: Hormonal regulation of neuroprotection, development of therapies and biomarkers for stroke and Alzheimer’s disease, role of the blood brain barrier and neural support cells in the pathophysiology of stroke.

TARCC Scientific Committees: Steering Committee

Dr. Sohrabji's Publications on PubMed


Texas Tech University Health Sciences Center, Lubbock

Chuang-Kuo Wu, M.D., Ph.D.Chuang-Kuo Wu, M.D., Ph.D. Dr. Chuang-Kuo Wu is the Corinne Payne Wright Regents Endowed Chair in Alzheimer’s Disease at Texas Tech University Health Sciences Center School of Medicine and an Associate Professor in the Department of Neurology as well as the Department of Pharmacology and Neuroscience. Dr. Wu earned his Ph.D. degree in behavioral neuroscience from Boston University School of Medicine and completed his neurology residency training at Boston University Medical Center. Mentored by Dr. Leon Thal, Dr. Wu finished his specialty training in Alzheimer research and associated dementia disorders at the University of California, San Diego - Alzheimer’s Disease Research Center (ADRC) and Alzheimer’s Disease Cooperative Study (ADCS) Group. Dr. Wu has participated in clinical studies and conducted clinical trials for Alzheimer’s disease, funded by NIH and industry. Dr. Wu has published original papers on several major topics of Alzheimer research, including animal models of aging and Alzheimer’s disease, neurodegeneration of the human cholinergic system and clinical trials.

Primary Research Interests:  Aging of the human cholinergic system. Therapeutics of Alzheimer’s disease and other dementias.

TARCC Scientific Committees: Steering Committee



The University of Texas Health Sciences Center at San Antonio

Donald R. Royall, M.D.Donald R. Royall, M.D., is Chief of the Division of Aging and Geriatric Psychiatry, the Julia and Van Buren Parr Professor of Geriatric Psychiatry, and a professor in the departments of Medicine and Pharmacology at The University of Texas Health Science Center at San Antonio. Dr. Royall has developed two widely used Executive Cognitive Function measures, CLOX: An Executive Clock-drawing Task and the Executive Interview (EXIT25), which are important predictors of independent living skills, decision making and adherence to treatment. Dr. Royall is an investigator in the Women’s Health Initiative and the Hispanic Established Population for Epidemiological Studies in the Elderly (HEPESE). He also supervises residents and geriatric fellows at the Audie L. Murphy Memorial Veterans Hospital’s Geriatric Research Education and Clinical Center. Dr. Royall received his medical degree from The University of Texas Health Science Center at Houston and completed residency training in both Internal Medicine and Psychiatry at the Johns Hopkins Hospital in Baltimore, MD.


Primary Research Interests: Cognitive predictors of mortality focusing on conditions that affect right hemisphere brain functions, including stroke, Alzheimer’s disease (AD), Lewy Body disease (LBD) and normal aging.

TARCC Scientific Committees: Steering Committee, Neuropsychology Subcommittee
Curriculum Vitae


The University of Texas Southwestern Medical Center, Dallas

Perrie M. Adams, Ph.D. Perrie M. Adams, Ph.D., is the Associate Dean for Research and the Margaret D. Harris Professor in Alzheimer's Research in the Department of Psychiatry at The University of Texas Southwestern Medical Center at Dallas. He is also Acting Chair of the Department of Biomedical Communications. Currently, Dr. Adams is co-principal investigator for the Alzheimer's Disease Center at Southwestern and for the National Institutes of Health Clinical Research Curriculum Program in Patient-Oriented Research. He is a long-time member and former Chairman of Southwestern Medical Center's Institutional Review Board. Dr. Adams received his Ph.D. in Psychology from Florida State University and previously taught in the Departments of Psychiatry and Behavioral Sciences and Pharmacology and Toxicology at The University of Texas Medical Branch in Galveston.

Primary Research Interests: Alzheimer's disease, genetic toxicology, developmental biology

TARCC Scientific Committees: Steering Committee
Curriculum Vitae


University of North Texas Health Science Center, Fort Worth

Thomas J. Fairchild, Ph.D. Thomas J. Fairchild, Ph.D., is Vice President of the Office of Strategy and Measurement at the University of North Texas Health Science Center at Fort Worth. He is also a member of the health science center's Information Resources Advisory Council and a faculty member of the School of Public Health. Since 1997, Dr. Fairchild has served as Director of Special Projects on Aging and, from 1997 to 2003, directed the Geriatrics Education and Research Institute at the University of North Texas Health Science Center. He currently serves on the Board of The Institute for Optimal Aging and is a past delegate to the White House Conference on Aging. He completed his Ph.D. in Sociology with a specialization in aging from Wayne State University.

Primary Research Interests: Gerontology with an emphasis on retirement housing, long-term care, and health services management

TARCC Scientific Committees: Steering Committee
Dr. Fairchild's Publications on PubMed
Curriculum Vitae



TARCC Scientific Manager

Robert Barber, Ph.D.Robert Barber, Ph.D., an Associate Professor at The University of North Texas Health Science Center in Fort Worth & Adjunct Faculty member at The University of Texas Southwestern Medical Center in Dallas is the Scientific Manager for the Texas Alzheimer's Research and Care Consortium. Dr. Barber's research efforts focus on identifying biomarkers and genetic variation that impacts risk for complex human disease. Dr. Barber earned a Masters of Science degree in Marine Biology and a Ph.D. in genetics from Texas A&M University. After a post-doctoral fellowship, he served as an Assistant Professor at the University of Nebraska Medical Center. He joined the faculty of UT Southwestern Medical Center in 2002, where he served as the Assistant Director of the Burn Research Center. He joined the Department of Pharmacology and Neuroscience at the University of North Texas Health Science Center in 2010.


Primary Research Interests: The role of mitochondrial genetic variation in the development of Alzheimer’s disease, racial and ethnic differences in Alzheimer’s risk and the link between inflammation and dementia.

TARCC Scientific Committees: Steering Committee, Genetics Subcommittee (Chair), Biomarker Subcommittee, Neuropsychology Subcommittee, Publication Subcommittee (Chair)

Alzheimer's disease, genetic toxicology, developmental biology

 





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Alzheimer's Facts

The Alzheimer’s Association estimates that there are 200,000 individuals younger than 65 with younger-onset Alzheimer’s disease.